Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

731
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
731
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

529
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
529
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

404
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
404
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

1.0K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.0K
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

374
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
374
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

918
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
918

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

sQuiz your knowledge! Multiple yellowish papules in an adult.

European journal of dermatology : EJD·2026
Same author

Effects of digoxin in modern heart failure treatment: Rationale and design of the DIG-Mod HF trial.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology·2026
Same author

Clinical and procedural outcomes of very high-power short-duration vs. standard power ablation for pulmonary vein isolation.

Frontiers in cardiovascular medicine·2026
Same author

Modulation of interbrain synchrony by emotional valence and maternal presence in mother-child dyads: neural links to empathy and attachment.

Scientific reports·2026
Same author

From clear indications to gray zones: The real-world challenge of patent foramen ovale closure.

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology·2026
Same author

Peripheral Blood Cells and Clinical Profiles as Biomarkers for Pain Detection in Palliative Care Patients.

Biomedicines·2026

Related Experiment Video

Updated: Mar 10, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.8K

Bicuspid aortic valve outcomes.

Inês Rodrigues1, Ana F Agapito1, Lídia de Sousa1

  • 1Department of Cardiology,Centro Hospitalar de Lisboa Central,Hospital de Santa Marta,Lisbon,Portugal.

Cardiology in the Young
|December 13, 2016
PubMed
Summary
This summary is machine-generated.

Adults with bicuspid aortic valve have excellent long-term survival but frequently experience cardiovascular events. Baseline aortic valve calcification and dysfunction predict these events.

Keywords:
bicuspidcongenitalAortaaortic valveheart defectssurvival

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.6K

Related Experiment Videos

Last Updated: Mar 10, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.8K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.6K

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Aortic Valve Disease

Background:

  • Bicuspid aortic valve is the most common congenital heart defect.
  • It is associated with valvular dysfunction, endocarditis, thoracic aorta dilatation, and dissection.

Purpose of the Study:

  • To assess the incidence of cardiac events in adults with bicuspid aortic valve.
  • To identify predictors of cardiac events in this population.

Main Methods:

  • Retrospective analysis of cardiac outcomes in ambulatory adults with bicuspid aortic valve.
  • Follow-up in a tertiary hospital center.
  • Kaplan-Meier curves and multivariate analysis were used.

Main Results:

  • 227 patients were followed for 13±9 years.
  • 38.8% experienced at least one cardiac outcome; 20-year incidence was 47±4%.
  • Baseline moderate-severe aortic valve dysfunction and calcification predicted composite endpoint.

Conclusions:

  • Long-term survival in bicuspid aortic valve patients is excellent.
  • Frequent cardiovascular events occur, with calcification and dysfunction as key predictors.