Related Experiment Video
Updated: Mar 10, 2026

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
Published on: May 16, 2025
[Review of numerical simulation study of Stanford type B thoracic aortic dissection]
1State Key Laboratory of Clean Energy Utilization, Zhejiang University, Hangzhou 310027, China.
Abstract:
According to the previous studies, some key indicators such as the hemodynamic parameters (pressure, flow rate, shear stress, etc.) as well as the geometry and the location of tear are closely related to the development of aortic dissection but are hard to measure in vivo. With the help of computational fluid dynamic method, a promising way is just shown to investigate the mechanisms and treatment of aortic dissection from the perspective of hemodynamics by constructing a three-dimensional model to simulate blood flow. This paper presents a systematic review of the development of aortic dissection research and the major research progress of computational fluid dynamics applied to the analysis of aortic dissection.

