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Updated: Mar 10, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Frequency of unplanned interventions in patients attending for a presumed routine glaucoma follow-up appointment
Jennifer Calafati1, Zia S Pradhan1, Catherine M Birt2
1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.
Objective:
To determine the frequency of patient visits in which an unplanned treatment modification was required in chronic patients attending a glaucoma clinic for routine follow-up and to identify the treatment interventions most commonly employed.
Design:
Prospective, cross-sectional study.
Participants:
A total of 630 previously stable patients attending a glaucoma clinic for routine follow-up.
Methods:
This was a single-centre survey of all eligible patients returning to an academic glaucoma clinic. Data regarding whether patients' visit remained routine or required intervention, which clinical parameter had changed, and any alterations in treatment regimens were studied.
Results:
The percentage of patients found to require a change in management was 20.79% (131 of 630 patients); 16.9% were found to have a cause for change because of glaucoma, and the remaining 4% required intervention because of a nonglaucomatous condition. The most common parameter that changed treatment was intraocular pressure (43.87%), followed by visual fields (21.29%). The frequency of abnormal parameters varied within each subtype of glaucoma. The frequency of treatment changes among those with primary open-angle glaucoma was 22.58% compared with 16.5% of glaucoma suspects, 14% of ocular hypertensives, 32% of pseudoexfoliative glaucoma, and 50% of normal tension glaucoma patients. The most common intervention (32.84%) was a change in antiglaucoma medications. The next most frequent interventions were laser procedures (21.90%) and surgery (16.06%).
Conclusions:
This study suggests that a significant minority of patients attending a glaucoma clinic for a routine appointment require treatment modification.
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