Related Experiment Video
Updated: Mar 10, 2026

A Multi-detection Assay for Malaria Transmitting Mosquitoes
Published on: February 28, 2015
Phylogenetic relationship and genotypic variability in Anaplasma marginale strains causing anaplasmosis in India
Neena George1, Vasundhra Bhandari1, Paresh Sharma1
1National Institute of Animal Biotechnology-DBT, Hyderabad, India.
Abstract:
Anaplasma marginale is a tick borne rickesttsial parasite known to cause bovine anaplasmosis. There are prevalence reports from different parts of India, however, information regarding genetic diversity and phylogenetic association of the Indian strains are unknown. In the current study, 965 cattle blood samples from two states of India, Seemandhra and Telangana, were investigated for the presence of A. marginale by PCR using major surface protein 4 gene (msp4). We found an overall infection of 16.4%, with 3.4% prevalence in Seemandhra and 22.2% in Telangana. Sequence analysis of the 24 cloned msp4 gene indicated genetic diversity among Indian clinical strains of A. marginale which may be due to evolutionary pressure or migration of strains. Phylogenetic association analysis revealed that most of the strains showed close proximity with strains from Mexico and other strains showed closeness to strains reported from countries like Brazil, Zimbabwe, Prico and Hungary. This is the first report from India, identifying heterogeneous population of A. marginale strains causing anaplasmosis, and such data can play an important role in designing new control policies.
More Related Videos
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Bacterial Phylum Tenericutes
Modern Molecular Taxonomy
Diversity of Protists II

