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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
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Perioperative cognitive protection.

C Brown1, S Deiner2,3,4

  • 1Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Sheikh Zayed Tower, 1800 Orleans Street, Baltimore, MD 21287, USA.

British Journal of Anaesthesia
|December 13, 2016
PubMed
Summary
This summary is machine-generated.

Older surgical patients often experience temporary cognitive decline. This review summarizes current evidence on postoperative delirium and cognitive dysfunction to guide clinical practice.

Keywords:
cognitiondeliriumperioperative periodsurgery

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Area of Science:

  • Geriatric Medicine
  • Neuroscience
  • Anesthesiology

Background:

  • Cognitive impairment is common in older adults post-surgery.
  • Postoperative delirium and postoperative cognitive dysfunction are key concerns.
  • Existing evidence guides clinical practice despite ongoing research needs.

Purpose of the Study:

  • To review the current understanding of cognitive dysfunction after surgery.
  • To synthesize information from interdisciplinary groups.
  • To provide evidence-based guidance for practitioners.

Main Methods:

  • Literature review of cognitive changes in surgical patients.
  • Synthesis of findings from interdisciplinary stakeholder groups.
  • Analysis of current evidence on delirium and cognitive dysfunction.

Main Results:

  • Significant evidence supports transient cognitive decline in older surgical patients.
  • Delirium is a costly public health issue.
  • Postoperative cognitive dysfunction is a recognized research construct.

Conclusions:

  • Best-practice clinical evidence is needed for managing postoperative cognitive issues.
  • An emerging body of literature can inform practitioners.
  • Further high-level evidence is required to refine clinical guidelines.