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Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Globalizing and crowdsourcing biomedical research.

Ebrahim Afshinnekoo^1,2,3, Sofia Ahsanuddin^1,2,4, Christopher E Mason^5,2,6

¹Department of Physiology and Biophysics, Weill Cornell Medicine, 1300 York Ave, New York, NY 10021, USA.

British Medical Bulletin

|December 13, 2016

Summary

This summary is machine-generated.

Crowdfunding and crowdsourcing revolutionize medical research by enabling large-scale data collection for discoveries in RNA, microbiome, and personalized medicine. Ensuring data rigor is key for these citizen-science initiatives.

Keywords:

citizen scientist crowdfunding genome metagenome microbiome

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Area of Science:

Biomedical research
Genomics
Citizen science

Background:

Crowdfunding and crowdsourcing offer novel paradigms for medical research, enabling rapid data collection and interpretation for high-throughput experiments.
These approaches have led to significant discoveries in RNA mechanisms, microbiome dynamics, and patient interpretation of results.
However, successful implementation requires robust training, uniform sampling, and experimental rigor.

Purpose of the Study:

To review scientific studies utilizing crowdsourcing and crowdfunding for data generation.
To discuss experiences in citizen-science research initiatives (MetaSUB and PathoMap) focusing on data robustness, educational outreach, and public engagement.

Main Methods:

Comprehensive literature review of crowdsourcing and crowdfunding in scientific studies.
Discussion of practical experiences from citizen-science initiatives like MetaSUB and PathoMap.

Main Results:

Crowdsourcing effectively revolutionizes microbiome and metagenomic research, enhancing the understanding of microbial and genetic dynamics globally.
Crowdsourced studies provide unprecedented capabilities for monitoring and measuring changes at microbial and macroscopic scales.
These strategies have transformed genomics research, fostering global citizen-science initiatives and leading to new discoveries.

Conclusions:

Crowdsourced data facilitate advancements in personalized medicine by empowering community members to contribute to personal and environmental health data.
Crowdsourced viral and metagenomic studies represent a critical next step for characterizing urban population health at genomic and epigenomic levels.