Related Experiment Video
Updated: Mar 10, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
Targeted response? An exploration of why ambulance services find government targets particularly challenging
Mark Durham1, Mark Faulkner2, Charles Deakin3
1Critical Care Paramedic, South East Coast Ambulance Service, Brighton Ambulance Station, BN2 3EU, Elm Grove Brighton Mark.Durham@secamb.nhs.uk.
Introduction Or Background:
Ambulance services have historically found their targets particularly challenging. This article explores some areas of this multifaceted problem.
Sources Of Data:
Research articles, government publications and published audit data.
Areas Of Agreement:
Demand is increasing in many areas of healthcare, but whilst hospitals saw a 7% increase in demand in recent times, ambulance services saw nearly double that. The services ambulance trusts provide have evolved from that of a transport service to that of a mobile health provider, and they have become victims of their own success.
Areas Of Controversy:
Ambulance targets have never evolved to match evolving care. Ambulance personnel strive to avoid hospital attendance where appropriate, but this can be difficult for a 24-hour service, when not all referral pathways have 24-hour referral systems.
Growing Points:
We discuss why demand might be growing disproportionately for ambulance services, and challenge the appropriateness of the targets themselves.
Areas Timely For Developing Research:
Possible formats for revised ambulance targets are discussed.
More Related Videos
08:59Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
Published on: December 11, 2017
08:52Profiling Sensitivity to Targeted Therapies in EGFR-Mutant NSCLC Patient-Derived Organoids
Published on: November 22, 2021
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Tumor Immunotherapy
Modified-Release Drug Delivery Systems: Site-Targeted
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Treatment Resistant Cancers