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A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection
Shuopeng Liu1, Wenqiong Su2, Xianting Ding3
1Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. spliu613@sjtu.edu.cn.
Sensors (Basel, Switzerland)
|December 13, 2016
Summary
Microfluidic Paper-based Analytical Devices (μPADs) offer a sensitive, rapid, and cost-effective solution for glucose detection. This review highlights recent advancements in colorimetric and electrochemical μPADs for improved disease monitoring.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Materials Science
Background:
- Glucose is vital for metabolic processes and linked to diseases like diabetes and islet cell carcinoma.
- Accurate, rapid, and cost-effective glucose detection methods are crucial for disease management.
- Microfluidic Paper-based Analytical Devices (μPADs) offer portability and minimal sample requirements for glucose sensing.
Purpose of the Study:
- To review recent advancements in glucose detection using μPADs.
- To summarize improvements in both colorimetric and electrochemical μPADs for glucose sensing.
- To highlight fabrication techniques for μPAD channels.
Main Methods:
- Review of recent literature on colorimetric and electrochemical μPADs for glucose detection.
- Analysis of progressive channel fabrication techniques for μPADs.
- Synthesis of key findings on μPAD performance and applications.
Main Results:
- Recent progress in colorimetric μPADs demonstrates enhanced sensitivity and accuracy.
- Electrochemical μPADs show significant improvements in response time and detection limits.
- Advanced fabrication methods enable more sophisticated and reliable μPAD designs.
Conclusions:
- μPADs are a promising technology for sensitive, rapid, and cost-effective glucose detection.
- Continued development in μPADs, particularly for colorimetric and electrochemical methods, is essential.
- Low-cost, commercial μPADs will be in high demand for managing glucose-related diseases globally.
