Povidone-Iodine Irrigation of Subcutaneous Tissues May Decrease Surgical Site Infections in Elective Colorectal
Richdeep S Gill1, David P Al-Adra1, Sandy Campbell2
1Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Gastroenterology Research
|December 13, 2016
Summary
Intra-operative Povidone-Iodine (PVI) irrigation of subcutaneous tissue after colorectal surgery significantly reduces surgical site infections. Further research is recommended due to the limited number of studies and patients included in this review.
Area of Science:
- Surgical Site Infections
- Colorectal Surgery
- Antiseptic Efficacy
Background:
- Postoperative wound infection is a common complication after abdominal surgery, increasing morbidity and hospital stay.
- Povidone-Iodine (PVI) is a broad-spectrum antiseptic used intra-operatively.
- Systematic review on PVI irrigation for subcutaneous tissues in elective colorectal surgery.
Purpose of the Study:
- To systematically review the literature on the efficacy of intra-operative PVI irrigation of subcutaneous tissues.
- To assess the impact of PVI on reducing surgical site infections in colorectal surgery patients.
Main Methods:
- Comprehensive search of electronic databases and grey literature, including unpublished and non-English studies.
- Inclusion of all clinical controlled trials involving PVI in adult colorectal surgery.
- Data extraction and quality assessment by two independent reviewers; relative risks and mean differences reported with 95% confidence intervals.
Main Results:
- Five randomized controlled trials (RCTs) with 205 patients were identified.
- Pooled results showed a reduced incidence of surgical site infection with PVI irrigation (RR = 1.97; 95% CI: 1.22 to 3.17).
Conclusions:
- Subcutaneous PVI irrigation after abdominal fascial closure reduces surgical site infection incidence.
- Additional robust randomized trials are needed due to the small number of included trials and patients.
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