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Using Robotic Systems to Process and Embed Colonic Murine Samples for Histological Analyses
Published on: January 7, 2019
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Improving the Yield of Histological Sampling in Patients With Suspected Colorectal Cancer During Colonoscopy by
Ahmed Gado1, Basel Ebeid2, Aida Abdelmohsen3
1Department of Medicine, Bolak Eldakror Hospital, Giza, Egypt.
Gastroenterology Research
|December 13, 2016
Summary
Implementing a colonoscopy quality assurance program significantly improved the diagnostic yield of biopsy samples for suspected colorectal cancer (CRC). This enhancement ensures more accurate diagnoses for patients undergoing colonoscopy.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Biopsy confirmation is crucial for suspected malignant masses.
- Diagnostic yield can be limited by non-viable tissue in biopsy samples.
- Multiple biopsy samples (BSs) improve diagnostic accuracy.
Purpose of the Study:
- To evaluate the impact of a colonoscopy quality assurance program (CQAP) on histological sampling yield.
- To assess changes in diagnostic accuracy for suspected colorectal cancer (CRC) post-CQAP implementation.
Main Methods:
- Initial assessment of colonoscopy practice in 2003 with 5 patients.
- Implementation of a quality improvement process requiring a minimum of six adequate biopsy samples (BSs).
- Prospective assessment of 37 patients from 2004-2010.
Main Results:
- The diagnostic yield for CRC ranged from 50% to 100% annually between 2004 and 2010.
- A significant increase in histological sampling yield was observed from 61% (2004-2007) to 92% (2008-2010) (p<0.02).
Conclusions:
- A quality assurance and improvement program demonstrably enhances histological sampling yield.
- Implementing CQAP protocols improves diagnostic accuracy for suspected colorectal cancer during colonoscopy.
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