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Updated: Mar 10, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

Highly efficient eigen decomposition based statistical optical microangiography.

Qinqin Zhang¹, Jingang Wang¹, Ruikang K Wang²

¹Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.

Quantitative Imaging in Medicine and Surgery

|December 13, 2016

Summary

This summary is machine-generated.

A new method called block-based eigen-decomposition (bED) enhances real-time blood flow imaging using optical coherence tomography (OCT). This technique improves contrast and saves computational power compared to traditional methods.

Keywords:

Optical coherence tomography (OCT)eigen-decomposition (ED)optical microangiography (OMAG)static signal and dynamic signal

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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

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Published on: February 18, 2022

Area of Science:

Biomedical Optics
Medical Imaging

Background:

Traditional voxel-based eigen-decomposition (vED) has limitations for real-time imaging of blood flow in living tissues.
There is a need for more efficient methods to visualize microvasculature dynamics.

Purpose of the Study:

To introduce a novel, efficient method for contrasting in vivo blood flow using optical coherence tomography (OCT).
To overcome the computational drawbacks of existing eigen-decomposition (ED) techniques for real-time applications.

Main Methods:

Proposed block-based eigen-decomposition (bED) applying ED filter on repeated complex-valued OCT B-scans.
Detailed the mathematical framework of bED.
Validated bED performance by imaging cerebral blood flow in a mouse model.

Main Results:

bED demonstrated superior contrast and signal-to-noise ratio for blood flow visualization compared to traditional ED.
Significant reduction in computational power was achieved with bED.
Vessel connectivity was effectively preserved and enhanced.

Conclusions:

Block-based eigen-decomposition (bED) is a practical and feasible method for achieving real-time OCT angiography.
The proposed ED approach is versatile and applicable to repeated A-scans and volumetric OCT data.