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Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets
Published on: September 13, 2017
NIR upconversion fluorescence glucose sensing and glucose-responsive insulin release of carbon dot-immobilized hybrid
Hui Wang1, Jinhui Yi1, Yanyan Yu1
1Department of Chemistry of The College of Staten Island of the City University of New York, Staten Island, NY 10314, USA. shuiqin.zhou@csi.cuny.edu and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, NY 10016, USA.
Abstract:
This work reports the preparation of multifunctional hybrid microgels based on the one-pot free radical dispersion polymerization of hydrogen-bonding complexes in water, formed from hydroxyl/carboxyl bearing carbon dots with 4-vinylphenylboronic acid and acrylamide comonomers, which can realize the simultaneous optical detection of glucose using near infrared light and glucose-responsive insulin delivery.
