Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Painless exercise ST deviation on the treadmill: long-term prognosis.

D B Mark1, M A Hlatky, R M Califf

  • 1Department of Medicine, Duke University Medical Center, Durham, North Carolina.

Journal of the American College of Cardiology
|October 1, 1989
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of obesity on outcome of unrelated cord blood transplant in children with malignant diseases.

Bone marrow transplantation·2010
Same author

Unrelated umbilical cord blood transplantation in children with immune deficiency: results of a multicenter study.

Bone marrow transplantation·2009
Same author

Relation between baseline risk and treatment decisions in non-ST elevation acute coronary syndromes: an examination of international practice patterns.

Heart (British Cardiac Society)·2005
Same author

Penalized maximum likelihood estimation to directly adjust diagnostic and prognostic prediction models for overoptimism: a clinical example.

Journal of clinical epidemiology·2004
Same author

Time-based risk assessment after myocardial infarction. Implications for timing of discharge and applications to medical decision-making.

European heart journal·2003
Same author

American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes. A report of the American College of Cardiology Task Force on Clinical Data Standards (Acute Coronary Syndromes Writing Committee).

Journal of the American College of Cardiology·2001

Silent ischemia during exercise testing in coronary artery disease patients is not benign but indicates an intermediate risk. These patients have less severe disease and a better prognosis than those with symptomatic ischemia.

Area of Science:

  • Cardiology
  • Exercise Physiology

Background:

  • Coronary artery disease (CAD) management relies on risk stratification.
  • Silent ischemia, identified during exercise testing, requires further evaluation for prognostic significance.

Purpose of the Study:

  • To assess the clinical features and long-term prognosis of silent ischemia during exercise in symptomatic CAD patients.
  • To compare outcomes between patients with no ischemia, silent ischemia, and symptomatic ischemia.

Main Methods:

  • Studied 1,698 symptomatic CAD patients undergoing treadmill testing and cardiac catheterization.
  • Classified patients into three groups: no ST deviation, painless ST deviation (silent ischemia), and angina with ST deviation.
  • Analyzed 5-year survival rates and clinical characteristics across groups.

Related Experiment Videos

Main Results:

  • Silent ischemia (painless ST deviation) showed a 5-year survival rate of 86%, similar to no ST deviation (88%).
  • Symptomatic ischemia (angina with ST deviation) had a significantly lower 5-year survival rate (73%).
  • Patients with silent ischemia had less aggressive anginal symptoms and less severe coronary artery disease than those with symptomatic ischemia.

Conclusions:

  • Silent ischemia during exercise testing in symptomatic CAD patients is an intermediate risk marker.
  • It signifies a less aggressive disease course and better prognosis compared to symptomatic ischemia.
  • This finding aids in refining risk stratification for patients with known coronary artery disease.