Related Experiment Video
Updated: Mar 10, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
Lateral hypothalamic control of metabolic factors related to feeding
1Laboratoire de Neurobiologie des Régulations C.N.R.S., Collège de France, Paris, France.
Abstract:
States of hunger and satiety are under ischymetric (i. e., rate of cellular energy production) control which depends on both substrate availability and hormonal composition. The latter varies in response to external (olfactory, gustatory and gastrointestinal) stimuli sensed by specific receptors and projected on lateral hypothalamic (LH) units from which departs the descendant control pathway of metabolic glands. This neurohormonal loop is responsible for the anticipatory glycemic and other changes observed during a meal and the preabsorptive "satiation" ending the meal long before the post-absorptive cellular repletion will induce the state of more permanent "satiety". New data on LH "sweet" taste projection and hypothalamo-pancreatic control are shown and strengthen the above view.
Related Concept Videos
Regulation of Food Intake
Diencephalon: Hypothalamus and Coordination
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
Primary Motives: Hunger and Thirst
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
Regulation of Metabolism
Feedback Loops
Hormonal Regulation

