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Evidence-based clinical practice guidelines for cholelithiasis 2016.

Susumu Tazuma1,2, Michiaki Unno3, Yoshinori Igarashi3

  • 1, Guidelines Committee for the Japanese Society of Gastroenterology ''Evidence-based clinical practice guidelines for cholelithiasis'', Hiroshima, Japan. stazuma@hiroshima-u.ac.jp.

Journal of Gastroenterology
|December 13, 2016
PubMed
Summary
This summary is machine-generated.

Revised clinical practice guidelines for cholelithiasis (gallstones) offer updated evidence-based recommendations for diagnosis and treatment. These guidelines incorporate recent advancements in endoscopic and surgical techniques for managing gallstone complications.

Keywords:
Bile acid dissolution therapyCholelithiasisEndoscopic sphincterotomyExtracorporeal shock wave lithotripsyLaparoscopic cholecystectomy

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Area of Science:

  • Gastroenterology
  • Clinical Practice Guidelines

Background:

  • Cholelithiasis (gallstones) is a prevalent gastroenterological condition.
  • Significant advancements have been made in therapeutic modalities for gallstones and their complications.

Purpose of the Study:

  • To present the revised evidence-based clinical practice guidelines for cholelithiasis by the Japanese Society of Gastroenterology.
  • To provide clinicians with updated recommendations for the diagnosis and management of cholelithiasis and its complications.

Main Methods:

  • Selection of 43 clinical questions across four categories: epidemiology/pathogenesis, diagnosis, treatments, and prognosis/complications.
  • Comprehensive literature search of MEDLINE, Cochrane, and Igaku Chuo Zasshi databases (1983-June 2012).
  • Development of guidelines using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.

Main Results:

  • The guidelines detail stepwise diagnosis using imaging modalities.
  • Treatment strategies for cholecystolithiasis, choledocholithiasis, and hepatolithiasis are presented with a flowchart.
  • Emphasis on flexibility in treatment choices based on clinical environment due to improved endoscopic and surgical techniques.

Conclusions:

  • The revised guidelines offer evidence-based, flexible approaches to cholelithiasis management.
  • These updated guidelines are suitable for daily clinical practice by healthcare professionals.
  • The guidelines reflect the latest improvements in endoscopic and surgical interventions for gallstone disease.