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Longitudinal function and ventricular dyssynchrony are restored in children with pulmonary stenosis after

Ragab A Mahfouz1, Tamer M Moustafa2, Mohammad Gouda1

  • 1Cardiology Department, Zagazig University Hospitals, Zagazig, Egypt.

The International Journal of Cardiovascular Imaging
|December 13, 2016
PubMed

Insights

Balloon pulmonary valvuloplasty effectively improved longitudinal ventricular function and cardiac synchrony in children with pulmonary stenosis (PS). Early intervention with this procedure helps prevent further cardiac deformation in pediatric patients.

Area of Science:

  • Pediatric Cardiology
  • Echocardiography
  • Congenital Heart Disease

Background:

  • Congenital moderately severe pulmonary stenosis (PS) can lead to ventricular dysfunction and cardiac dyssynchrony.
  • Assessing longitudinal function and synchrony is crucial for managing PS in children.

Purpose of the Study:

  • To evaluate the impact of balloon pulmonary valvuloplasty on longitudinal ventricular dysfunction and cardiac dyssynchrony in children with PS.
  • To determine if percutaneous balloon pulmonary valvuloplasty improves cardiac function and synchrony.

Main Methods:

  • Echocardiography with tissue Doppler imaging (TDI) was used to assess cardiac function and synchrony.
  • Key parameters included mitral annular plane excursion (MAPSE), tricuspid annular plane excursion (TAPSE), and systolic waves (LVs, RVs).
  • Measurements were taken before and after successful balloon pulmonary valvuloplasty in 48 children with PS and compared to 36 controls.

Main Results:

  • Children with PS showed significantly lower TAPSE, RVs, TAPSE/MAPSE, and RVs/LVs ratios compared to controls.
  • Intra- and inter-ventricular dyssynchrony were significantly increased in PS patients.
  • Balloon pulmonary valvuloplasty significantly improved all measured parameters, restoring longitudinal function and synchrony.

Conclusions:

  • Percutaneous balloon pulmonary valvuloplasty is effective in restoring longitudinal cardiac function and synchrony in children with valvular PS.
  • Early intervention is important to prevent the progression of cardiac deformation in pediatric pulmonary stenosis.
  • This study highlights the benefits of timely valvuloplasty for improving cardiac outcomes in children with PS.

Keywords:
DyssynchronyLongitudinal functionPulmonary stenosisValvuloplasty

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