Microbiological evaluation of MiraFlow

The antimicrobial activity of MiraFlow, an extra-strength cleaner containing 20% isopropyl alcohol, was evaluated using various microorganisms including Acanthamoeba. Other leading cleaners, disinfecting solutions and heat were evaluated for comparison. MiraFlow had greater antimicrobial activity than the other cleaning solutions against all five test microorganisms. When evaluated against Acanthamoeba castellanii, MiraFlow was significantly better than disinfecting solutions containing 3% hydrogen peroxide, with D-values of less than 12 seconds and 1 hour, respectively. Thermal disinfection of Acanthamoeba cysts occurred rapidly at temperatures above 60 degrees C. The data suggest that either thermal disinfection or cleaning lenses for 20 seconds with MiraFlow followed by disinfection in an amoebacidal solution such as 3% hydrogen peroxide, should inactivate Acanthamoeba cysts found as chance contaminants on lenses.