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Updated: Mar 10, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

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An Unconventional Acid-Labile Nucleobase Protection Concept for Guanosine Phosphoramidites in RNA Solid-Phase

Lukas Jud1, Ronald Micura1

  • 1Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|December 13, 2016
PubMed

Keywords:
RNAnucleosidesoligonucleotidesprotecting groupssolid-phase synthesis

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