Related Experiment Video
Updated: Jul 25, 2026

12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Suppurative extensor tenosynovitis caused by Staphylococcus aureus
E D Newman1, T M Harrington, D Torretti
1Department of Rheumatology and Orthopaedics, Geisinger Medical Center, Danville, Pa 17822.
The Journal of Hand Surgery
|September 1, 1989
Summary
Suppurative tenosynovitis, a rare infection, typically affects flexor tendons. This case highlights extensor tendon involvement due to Staphylococcus aureus, emphasizing early diagnosis to prevent complications.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Bacteriology
Background:
- Suppurative tenosynovitis is an uncommon infection, predominantly seen in flexor tendon sheaths following trauma.
- Staphylococcus aureus is a common pathogen, but extensor tendon sheath infections are rare.
Observation:
- A systemically ill female patient presented with an unusual case of suppurative tenosynovitis.
- The infection involved the extensor tendons, a site rarely affected by this condition.
Findings:
- The causative agent was identified as Staphylococcus aureus.
- This case represents a rare presentation of suppurative tenosynovitis in the extensor tendon sheath.
Implications:
- Early recognition of extensor tendon suppurative tenosynovitis is crucial for prompt treatment.
- Timely diagnosis and intervention can prevent significant morbidity associated with this rare infection.
More Related Videos
Related Concept Videos
Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Streptococcal Pharyngitis
Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Mechanism of Antibiotic Resistance in MRSA
Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and acquisition...
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

