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HBSAg antigenaemia in bilharzial patients
Journal of the Egyptian Society of Parasitology
|December 1, 1989
Insights
Hepatitis B surface antigen (HBSAg) was more common in patients with bilharzia (7%) compared to those without (2-5%). Liver damage from bilharzia or other causes did not affect HBSAg incidence in bilharzial patients.
Area of Science:
- Hepatology
- Infectious Diseases
- Parasitology
Background:
- Hepatitis B virus (HBV) infection is a significant global health concern.
- Bilharzia (schistosomiasis) is a chronic parasitic disease affecting millions worldwide.
- The interplay between parasitic infections and viral hepatitis requires further investigation.
Purpose of the Study:
- To determine the prevalence of Hepatitis B surface antigen (HBSAg) in patients with and without bilharzia.
- To assess the impact of liver lesions (bilharzial, chronic persistent hepatitis, chronic active hepatitis) on HBSAg incidence.
Main Methods:
- Serological testing for HBSAg in patient sera.
- Classification of patients based on bilharzia status and presence of liver lesions.
Main Results:
- The frequency of HBSAg was significantly higher in bilharzial patients (7%) than in non-bilharzial patients (2-5%).
- The presence of bilharzial liver disease, chronic persistent hepatitis, chronic active hepatitis, or combinations thereof did not alter HBSAg incidence in bilharzial patients.
Conclusions:
- Bilharzia infection is associated with a higher prevalence of HBSAg.
- Existing liver damage, regardless of cause, does not appear to influence HBSAg occurrence in the context of bilharzia.
Abstract:
The frequency of HBSAg in bilharzial patients (7%) was significantly higher than that in non bilharzial ones (2-5%). The presence of insulted liver by bilharzial, non bilharzial (C.P.H. and C.A.H.) or both (C.P.H. with bilharzia and C.A.H. with bilharzia) lesions have no role in changing the incidence of HBSAg in sera of bilharzial patients.