Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Vascularized intercostal nerve transfer--an experimental study].

N Nakamura1

  • 1Department of Orthopaedic Surgery, Jikei University School of Medicine, Tokyo, Japan.

Nihon Seikeigeka Gakkai Zasshi
|May 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protein kinase C isozyme expression in human leukemia-lymphoma cell lines--an immunocytochemical study.

Hematological oncology·1992
Same author

A simple and rapid method for HLA-DQA1 genotyping by polymerase chain reaction-single strand conformation polymorphism and restriction enzyme cleavage analysis.

Electrophoresis·1992
Same author

[Pheochromocytoma discovered in a pregnant woman: a case report].

Hinyokika kiyo. Acta urologica Japonica·1992
Same author

The potentiating effect of KC-404 on prostacyclin-induced vasodilation in isolated human cerebral artery.

General pharmacology·1992
Same author

Effects of malnutrition on development of experimental pressure sores.

The Journal of dermatology·1992
Same author

[The pattern of neurological deterioration and the mechanism of neurological deficit in syringomyelia].

Rinsho shinkeigaku = Clinical neurology·1992
Same journal

[20 years' experience with Charnley low friction arthroplasty--striving for durability and future prospects].

Nihon Seikeigeka Gakkai zasshi·1998
Same journal

[Orthotic treatment].

Nihon Seikeigeka Gakkai zasshi·1998
Same journal

[Recent status of basic research of orthopedics in Japan].

Nihon Seikeigeka Gakkai zasshi·1998
Same journal

[Reconstruction of efferent and afferent innervation of biceps muscle by the intercostal nerve].

Nihon Seikeigeka Gakkai zasshi·1998
Same journal

[Treatment of proximal humeral fractures].

Nihon Seikeigeka Gakkai zasshi·1998
Same journal

[Facts and concepts in bone and soft tissue tumor pathology].

Nihon Seikeigeka Gakkai zasshi·1998
See all related articles

Maintaining blood supply to the intercostal nerve is crucial for axonal regeneration and skeletal muscle recovery after nerve transfer surgery. Vascularized nerve transfers promote better muscle healing and nerve regrowth.

Area of Science:

  • Neurosurgery
  • Regenerative Medicine
  • Muscle Physiology

Context:

  • Intercostal nerve transfers are utilized for brachial plexus reconstruction.
  • Nerve viability and regeneration are critical for functional recovery.
  • The role of vascularization in nerve graft success requires further elucidation.

Purpose:

  • To investigate the impact of vascularized intercostal nerve detachment on axonal regeneration.
  • To assess the effect of vascularized versus unvascularized intercostal nerve transfer on skeletal muscle recovery.

Summary:

  • Detachment of the intercostal nerve without its accompanying blood vessels led to significant axonal degeneration and reduced blood flow.
  • In contrast, vascularized intercostal nerves showed no significant axonal degeneration.

Related Experiment Videos

  • Post-transfer, vascularized nerve transfers resulted in superior biceps brachii muscle regeneration (wet weight) compared to unvascularized transfers.
  • Histochemical analysis revealed shifts in muscle fiber type composition over time, with type 1 fibers becoming predominant by six months in vascularized transfers.

    • Impact:

    • This study highlights the critical importance of preserving vascularity during intercostal nerve harvest for successful nerve regeneration.
    • Findings suggest that vascularized nerve transfers enhance skeletal muscle recovery, offering improved outcomes for patients undergoing reconstructive surgery.
    • The results provide evidence supporting the use of vascularized nerve grafts in clinical practice to optimize functional restoration.