Functional voiding disorders in women

From July 1986 to Dec 1987, 78 women complaining of frequency, urgency, dysuria and suprapubic discomfort were evaluated at our clinic. Their ages ranged from 20 to 68 (mean age: 38.2). The patients who were noted to have evidence of pyuria, neurological or gynecological abnormalities were excluded from the study. Urodynamic examinations including uroflowmetry, cystometry (CMG), urethral pressure profiles (UPP) and electromyography (EMG) of the external urethral sphincter were performed. The results revealed low flow rates in 56 patients (71.8%), non-relaxation of the external sphincter during voiding in 55 patients (70.5%), unstable bladder in 6 patients (7.7%) and a high maximal urethral closure pressure (MUCP) (greater than 80 cmH2O) in 44 patients (56.4%). The average volume of the cystometric capacity (250 +/- 86 ml) was decreased. The association between the low flow rate, non-relaxation of the external sphincter and a high MUCP was statistically significant. Urethral hypersensitivity has been recognized as being the major cause of these symptoms.