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[Hemovigilance: State 2007-2013 Tunis].

S Mahjoub1, H Baccouche1, A Raissi1

  • 1Banque de sang de l'hôpital La Rabta, rue Jebel Lakhdar, Tunis, Tunisie.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|December 14, 2016
PubMed
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This study analyzed 120 transfusion adverse reactions over five years, finding hemolytic reactions most common. Improving reporting and training is crucial for blood transfusion safety.

Area of Science:

  • Transfusion Medicine
  • Patient Safety
  • Hemovigilance

Background:

  • Blood transfusion, while life-saving, carries inherent risks.
  • Hemovigilance systems are essential for monitoring and ensuring the safe use of blood components.
  • This study addresses the need for descriptive analysis of transfusion adverse reactions and system malfunctions.

Purpose of the Study:

  • To conduct a descriptive analysis of transfusion adverse reactions over a 5-year period.
  • To determine the incidence and etiology of adverse transfusion reactions.
  • To identify system malfunctions within the transfusion chain and propose corrective actions.

Main Methods:

  • Retrospective analysis of 120 reported transfusion adverse reactions at Hospital La Rabta.
Keywords:
Adverse reactionsHaemovigilanceHémovigilanceSécurité transfusionnelleTransfusion sanguine

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  • Inclusion of clinical and laboratory data for investigated transfusion accidents.
  • Classification of accidents based on severity and type.

    • Main Results:

    • Transfusion accident rates varied from 0.59 to 2.19 per 1000 labile blood products distributed.
    • The most frequent adverse reactions were hemolytic (19.8%), allergic (17.5%), and non-hemolytic feverish reactions (15.8%).
    • Grade 1 severity reactions were most common (n=94), with severe reactions (grades 3 and 4) also documented.

    Conclusions:

    • Significant lessons can be learned from the analyzed transfusion reaction data.
    • Identified system failures include under-reporting of adverse events and malfunctions in the transfusion chain.
    • In-service training is recommended to improve the accurate reporting and management of transfusion reactions.