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Gastrointestinal transit scintigraphy in chronic constipation evaluation in pediatric age; an infrequent test
J R Infante1, J I Rayo1, J Serrano1
1Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
Insights
Gastrointestinal transit scintigraphy is a valuable tool for diagnosing chronic constipation in children, offering accurate physiological and quantitative data. This method aids in clarifying diagnoses and guiding treatment when other tests are inconclusive.
Area of Science:
- Pediatric Gastroenterology
- Nuclear Medicine Imaging
Background:
- Chronic constipation affects many children, often requiring advanced diagnostic methods.
- Gastrointestinal transit scintigraphy offers a unique approach to evaluating bowel motility.
Observation:
- Five pediatric patients with refractory chronic constipation were studied.
- A comprehensive scintigraphy protocol assessed gastric emptying and small/large bowel transit times.
Findings:
- All patients exhibited abnormal scintigraphy results, contrasting with normal radiological tests in four.
- Scintigraphy altered or clarified diagnoses in three patients, influencing management in two.
- This technique provides reproducible, quantitative, and physiological data on gastrointestinal transit.
Implications:
- Gastrointestinal transit scintigraphy is a reliable method for pediatric constipation assessment.
- It offers advantages over other imaging techniques by providing global and regional transit time data.
- This diagnostic tool can significantly impact treatment strategies for pediatric constipation.
Aim:
Chronic constipation is a common pathology in children. The aim of this paper was to show the usefulness of gastrointestinal transit scintigraphy in pediatric patients with chronic constipation, and the advantages with respect to other imaging techniques, despite our limited experience.
Material And Methods:
We evaluated 5 patients sent to our service with a diagnosis of chronic constipation refractory to treatment. We performed a complete study protocol, including liquid gastric emptying scintigraphy and small and large bowel transit times, using a single dose of 111In-DTPA. Following international guidelines regions of interest were defined in stomach, terminal ileum and in 6 regions of the large intestine.
Results:
All patients showed altered scintigraphy study, showing 4 of them normal radiological tests. Radioisotopic study changed diagnosis in 2 patients and in other 2 patients contributed to clarify it, since discordance between normal radiological tests and abnormal rectal biopsy. One of the patients showed concordance between each imaging modality. The results of the test changed the therapeutic management in 2 cases.
Conclusions:
Our limited experience coincides with published data in which scintigraphy study turns out to be a reproducible and accurate method. It provides physiological, quantitative and useful information in the study of constipation, being the unique exploration that allows both global and regional gastrointestinal transit time determination.
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