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The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo
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The Stroke Preclinical Assessment Network Multi-laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo

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Stroke And Bleeding Risk Assessment: Where Are We Now?

Mikhail S Dzeshka1, Gregory Y H Lip2

  • 1University of Birmingham Centre for Cardiovascular Sciences City Hospital, Birmingham B18 7QH, United Kingdom; Grodno State Medical University, Grodno, Belarus.

Journal of Atrial Fibrillation
|December 14, 2016
PubMed

Insights

Atrial fibrillation increases stroke risk, necessitating oral anticoagulants. This review details stroke and bleeding risk scores like CHA₂DS₂-VASc and HAS-BLED for effective thromboprophylaxis decisions.

Area of Science:

  • Cardiology
  • Thrombosis Management

Background:

  • Atrial fibrillation (AF) is a significant cardiovascular condition.
  • Ischemic stroke is a major complication of AF, requiring effective oral anticoagulant therapy for prevention.
  • Accurate risk assessment is crucial for guiding thromboprophylaxis decisions.

Approach:

  • This review provides an overview of current stroke and bleeding risk assessment scores.
  • It focuses on guideline-recommended scores: CHA₂DS₂-VASc for stroke risk and HAS-BLED for bleeding risk.
  • The article also explores future directions for enhancing risk prediction using clinical factors and biomarkers.

Key Points:

  • CHA₂DS₂-VASc score evaluates stroke risk in AF patients.
  • HAS-BLED score assesses bleeding risk in AF patients on anticoagulation.
  • Both scores aid in personalized thromboprophylaxis strategies.

Conclusions:

  • Risk assessment scores are essential tools for managing AF-related stroke risk.
  • Optimizing these scores with novel biomarkers and clinical factors can improve patient outcomes.
  • Effective thromboprophylaxis in AF requires careful consideration of individual stroke and bleeding risks.

Keywords:
Atrial FibrillationBleedingRisk AssessmentStroke

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