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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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A Review Of Clinical Trials On LARIAT Device

Payam Safavi Naeini1, Abdi Rasekh1

  • 1Department Of Cardiology (Drs.Abdi Rasekh And Safavi-Naeini), Texas Heart Insitute. Department Of Cardiology (Dr.Abdi Rasekh), Baylor College Of Medicine, Houston, Texas.

Journal of Atrial Fibrillation
|December 14, 2016
PubMed

Insights

Patients with atrial fibrillation (AF) face a higher stroke risk. Percutaneous left atrial appendage (LAA) ligation offers a stroke prevention method for those unable to use blood thinners.

Area of Science:

  • Cardiology
  • Vascular Surgery

Background:

  • Atrial fibrillation (AF) significantly increases embolic stroke risk (5x higher than general population).
  • Left atrial appendage (LAA) is the primary source (>90%) of thrombus formation in AF patients.
  • Oral anticoagulant therapy is contraindicated for some AF patients, necessitating alternative stroke prevention strategies.

Approach:

  • This review evaluates the efficacy and safety of percutaneous LAA ligation.
  • Focuses on LAA closure as a method to prevent thromboembolism in AF.

Key Points:

  • Percutaneous LAA ligation aims to reduce stroke risk in AF patients.
  • Assesses the safety and effectiveness of this minimally invasive ligation technique.
  • Addresses stroke prevention in AF patients with contraindications to anticoagulation.

Conclusions:

  • LAA ligation presents a viable alternative for stroke prevention in specific AF patient cohorts.
  • Further research may solidify LAA ligation's role in AF management.
  • Percutaneous closure of the LAA is a promising therapeutic avenue.

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