Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blank Solutions00:56

Blank Solutions

1.4K
A blank solution is a solution that does not contain the analyte, or the substance of interest being tested or measured. It is typically prepared using the same reagents and procedure as the sample solution but without adding the analyte. The primary purpose of preparing a blank solution is to account for any background interference or contamination that may affect the accuracy and reliability of the analytical method.
In some experimental cases, the reagents, solvents, or lab equipment used in...
1.4K
Blinding01:11

Blinding

4.0K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
4.0K
Blind Procedures02:07

Blind Procedures

13.8K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.8K
Truncation in Survival Analysis01:09

Truncation in Survival Analysis

677
Truncation in survival analysis refers to the exclusion of individuals or events from the dataset based on specific criteria related to the time of the event. This exclusion can happen in two primary forms: left truncation and right truncation.
Left truncation occurs when individuals who experienced the event of interest before a certain time are not included in the study. This is often due to a "delayed entry" into the study where only those who survive until a certain entry point are...
677
Naturalistic Observations02:30

Naturalistic Observations

17.9K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.9K
The Scientific Method02:40

The Scientific Method

66.7K
Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.
66.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybrid atrial fibrillation ablation in patients with persistent atrial fibrillation or failed catheter ablation.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2019
Same author

International practices in the dietary management of fructose 1-6 biphosphatase deficiency.

Orphanet journal of rare diseases·2018
Same author

A mechanistic investigation of the ruthenium porphyrin catalysed aziridination of olefins by aryl azides.

Dalton transactions (Cambridge, England : 2003)·2015
Same author

Patients undergoing elective coronary artery bypass grafting exhibit poor pre-operative intakes of fruit, vegetables, dietary fibre, fish and vitamin D.

The British journal of nutrition·2015
Same author

A pilot study of cerebral tissue oxygenation and postoperative cognitive dysfunction among patients undergoing coronary artery bypass grafting randomised to surgery with or without cardiopulmonary bypass*.

Anaesthesia·2014
Same author

Letter to the editor.

Journal of cardiovascular electrophysiology·2013
Same journal

The Importance of Atrial Fibrillation's Associated Comorbidities as Clinical Presentation and Outcome Contributors.

Journal of atrial fibrillation·2021
Same journal

The story of a Migrating Pericardial Drain and Perforation!

Journal of atrial fibrillation·2021
Same journal

Incidence of New Onset Atrial Fibrillation After Cardiovascular Surgery in Vietnam: Results From A Novel Screening Strategy.

Journal of atrial fibrillation·2021
Same journal

Effect of SLGT2 Inhibitors on Patients with Atrial Fibrillation.

Journal of atrial fibrillation·2021
Same journal

Same Day versus Overnight Discharge in Patients Undergoing Ablation for Atrial Fibrillation (SODA) Study.

Journal of atrial fibrillation·2021
Same journal

Biomarkers of Metabolic Syndrome: Role in Pathogenesis and Pathophysiology Of Atrial Fibrillation.

Journal of atrial fibrillation·2021
See all related articles

Related Experiment Video

Updated: Mar 10, 2026

Manual Blot-and-Plunge Freezing of Biological Specimens for Single-Particle Cryogenic Electron Microscopy
09:16

Manual Blot-and-Plunge Freezing of Biological Specimens for Single-Particle Cryogenic Electron Microscopy

Published on: February 7, 2022

7.5K

What Does The Blanking Period Blank?

M A Mariani1, A Pozzoli2, Ge De Maat1

  • 1University of Groningen, University Medical Center Groningen, Cardio-Thoracic Surgery Department, Groningen, The Netherlands.

Journal of Atrial Fibrillation
|December 14, 2016
PubMed
Summary
This summary is machine-generated.

The current 3-month blanking period after atrial fibrillation ablation is not evidence-based. A shorter, 4-week blanking period for pulmonary vein isolation is proposed due to early tissue healing and reduced arrhythmia risk.

Keywords:
Ablative TherapyAtrial FibrillationBlanking PeriodPulmonary Veins Isolation

More Related Videos

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research
08:12

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research

Published on: February 16, 2024

16.6K
A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline
09:00

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline

Published on: June 17, 2021

3.5K

Related Experiment Videos

Last Updated: Mar 10, 2026

Manual Blot-and-Plunge Freezing of Biological Specimens for Single-Particle Cryogenic Electron Microscopy
09:16

Manual Blot-and-Plunge Freezing of Biological Specimens for Single-Particle Cryogenic Electron Microscopy

Published on: February 7, 2022

7.5K
Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research
08:12

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research

Published on: February 16, 2024

16.6K
A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline
09:00

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline

Published on: June 17, 2021

3.5K

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Pulmonary vein isolation is a standard treatment for drug-refractory atrial fibrillation.
  • A 3-month "blanking period" is conventionally observed post-ablation, during which arrhythmias are not considered treatment failures.
  • This period is largely authority-based, lacking strong evidence.

Purpose of the Study:

  • To re-evaluate the optimal duration of the post-ablation blanking period.
  • To advocate for a shorter, evidence-based blanking period.

Main Methods:

  • Review of biological evidence regarding post-ablation tissue healing and arrhythmia mechanisms.
  • Analysis of the incidence and significance of early atrial tachyarrhythmias after ablation.

Main Results:

  • Atrial arrhythmias post-ablation are common (35-65%), with early recurrences influenced by acute inflammation and edema.
  • Tissue edema resolves by 1 month post-ablation.
  • Arrhythmias in the first month are more predictive of late recurrences.

Conclusions:

  • The current 3-month blanking period is not supported by current biological evidence.
  • A 4-week blanking period is proposed as more reasonable and clinically relevant.
  • This adjustment could foster a better understanding of ablation outcomes.