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Some Biochemical Markers in Patients with Alzheimer's Disease
Mohammad Khanahmadi1, Dariush D Farhud2, Maryam Malmir3
1Aging Research Center, Farhud Scientific-Cultural Foundation, Tehran, Iran.
Background:
Metal ions effect on homeostasis of Alzheimer's disease (AD) patients. The aim of this study was to assess the metal ions (Iron, Zinc and Copper) and CBC in patients with AD in comparison with normal range.
Methods:
The samples of study were 17 patients with AD in Tehran's aging centers in 2015, selected as an access sample. Blood samples were analyzed in a pathobiology laboratory. Data were analyzed by one sample t-test.
Results:
According to the normal range, provided by laboratory, there is a significant difference between zinc in patients with AD and normal reference interval (α=0.01). The comparison of CBC of the AD patients with normal group showed also some decreases.
Conclusion:
Zinc value in AD patients is significantly lower than normal range. It should be repeated by a larger sample size.
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