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Updated: Mar 10, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
[Screening, diagnosis and treatment of chronic hepatitis C in clinical practice]
Ezequiel Ridruejo1,2,3, Hugo Fainboim3,4, Alejandra Villamil3,5
1Sección Clínica Médica y Sección Hepatología, Departamento de Medicina Interna, Centro de Educación Médica e Investigaciones Clínicas, Norberto Quirno CEMIC, Buenos Aires, Argentina.
Abstract:
Chronic hepatitis C (HCV) is a global health problem. Worldwide, 170 million people are chronically infected. In Latin America its prevalence is estimated between 1.0 and 2.3%, and in Argentina between 1.0 and 1.5%. Treatment efficacy has considerably improved in the last 2 or 3 years. Sustained virological response (SVR) rates around 90-95% can be achieved with the new direct acting antiviral agents (DAAs) currently available, with few side effects. It is necessary to increase the number of diagnosed patients, linking them to adequate management and treatment. Raising treatment rates will increase the percentage of cured patients, reducing the burden of disease. Primary care physicians' role is essential to achieve this goal. They must identify persons at risk, diagnose them and work with specialists to continue their medical care. Team working of generalists and specialists will permit that more HCV infected people can access to adequate care and treatment.
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