Surgical Therapy
Insights
Surgical treatments for intracranial atherosclerosis, including angioplasty, stenting, and decompressive craniectomy, are reviewed. Their controversial benefits for stroke prevention in severe cases are discussed.
Area of Science:
- Neurology
- Neurosurgery
- Vascular Surgery
Background:
- Intracranial atherosclerosis is a significant cause of stroke.
- Medical management is primary, but surgical interventions are sometimes considered.
- The efficacy of surgical options for intracranial atherosclerosis remains debated.
Purpose of the Study:
- To review surgical therapies for intracranial atherosclerosis.
- To discuss the role and controversy of surgical interventions in managing stroke risk.
Main Methods:
- Literature review of surgical treatments for intracranial atherosclerosis.
- Focus on angioplasty, stenting, extracranial-intracranial (EC-IC) bypass, and decompressive craniectomy.
- Exclusion of EC-IC bypass for moyamoya disease.
Main Results:
- Angioplasty and stenting are used, but benefits can be limited.
- EC-IC bypass is considered for severe hemodynamic impairment.
- Decompressive craniectomy may reduce mortality in massive middle cerebral artery occlusions.
Conclusions:
- Surgical interventions for intracranial atherosclerosis present a complex treatment landscape.
- The benefits of surgical procedures, particularly EC-IC bypass, are controversial and require careful patient selection.
- Further research is needed to clarify the role of surgery in stroke prevention for this condition.
Abstract:
Many prior investigations have indicated the important role of medical treatment to prevent stroke in patients with intracranial atherosclerosis, with angioplasty and stenting occasionally being performed. In a subgroup of patients with severe hemodynamic impairment, extracranial-intracranial (EC-IC) bypass surgery may be considered. Additionally, in patients with massive infarctions due to middle cerebral artery (MCA) occlusion, the use of decompressive craniectomy may lower mortality rates and improve long-term quality of life. However, the benefit of these surgical procedures in patients with intracranial atherosclerosis has long been controversial. In this chapter, we review the surgical therapies for patients with intracranial atherosclerosis. This review does not include EC-IC bypass surgery for moyamoya disease, which is discussed in another chapter.
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