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Iatrogenic Catheter-Induced Acute Aortic Dissection Type A after Coronary Angiography-A Retrospective Consecutive
Katharina Huenges1, Jan Dreyer1, Bernd Panholzer1
1Department of Cardiovascular Surgery, University of Schleswig-Holstein Campus Kiel, Kiel, Germany.
Insights
Catheter-induced acute aortic dissection type A (ciAADA) is a rare but severe complication of coronary angiography. Patients with ciAADA face higher mortality rates due to pre-existing conditions and procedural complications.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Surgery
Background:
- Acute aortic dissection type A (AADA) is a life-threatening condition requiring complex surgical intervention.
- While typically spontaneous, AADA can arise as a complication of interventional procedures like coronary angiography.
Purpose of the Study:
- To analyze the characteristics and outcomes of patients who developed catheter-induced AADA (ciAADA) following coronary angiography.
- To compare the clinical presentation, surgical management, and mortality of ciAADA patients with the general AADA population.
Main Methods:
- Retrospective analysis of 14 patients surgically treated for ciAADA between 2004 and 2014.
- Comparison of ciAADA patient data with a cohort of 288 overall AADA patients from the same period.
Main Results:
- ciAADA patients were older, more frequently hemodynamically unstable, and required mechanical ventilation upon admission.
- Surgical procedures for ciAADA involved longer cardiopulmonary bypass and cross-clamp times, often necessitating coronary artery bypass grafting due to myocardial ischemia.
- ciAADA patients exhibited significantly higher 30-day mortality (50.0% vs. 10.7%) compared to the general AADA group.
Conclusions:
- Coronary angiography-induced AADA is a rare but serious complication with a poorer prognosis.
- Preoperative hemodynamic instability and the need for additional procedures contribute to the adverse outcomes observed in ciAADA patients.
Abstract:
Background Acute aortic dissection type A (AADA) is one of the most life-threatening situations and surgical demanding procedures even today. Usually AADA develops spontaneously, but it can be related also to interventional procedures. Methods We analyzed the data of 14 patients surgically treated in our institution with catheter-induced AADA (ciAADA) during coronary angiography between January 2004 and December 2014. Data were compared with overall AADA patients in this time period (n = 288). Results Nine of the 14 patients were female. Subjects were significantly older compared to the AADA patients (69 ± 11 vs. 62 ± 11; p = 0.021). At admission, ciAADA patients were more often hemodynamically instable and mechanically ventilated. Twelve patients underwent replacement of the ascending aorta and two patients received a modified Bentall operation. Cardiopulmonary bypass time (210 ± 92 vs. 172 ± 51 min) and cross-clamp time (122 ± 63 vs. 92 ± 40 min) were significantly longer due to additional coronary artery bypass grafts in 71.4 versus 3.1% due to myocardial ischemia. Operative mortality (7.1 vs. 2.1%, p = 0.29) and 30-day mortality (50.0 vs. 10.7%, p < 0.001) were higher in the ciAADA group. Conclusion Coronary angiography-induced AADA is a rare but severe complication. Due to additional myocardial ischemia and preoperative hemodynamic instability, patients with ciAADA have adverse outcome compared to overall AADA patients.
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