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Abstract:
Detailed and complete investigations for determining the tumor characteristic were made in 137 patients with bladder tumors. The study included: establishing the gross parameter (gross appearance, localization, size, multiplicity, mode of growth and dissemination), infiltration stage, degree of differentiation, cytophotometric parameters (ploidy and proportion of cells in S-phase) and immunologic data (indirect immunofluorescence and serum IgA and IgG levels). The results were correlated and a number of correlations between the individual qualities of the tumors were determined. On the basis of proven interrelations, staging and grading the two basic tendencies in tumor development--weak or strong malignancy--were outlined. Conclusions were drawn on the need of more detailed investigation of the correlations in bladder tumors, in order to facilitate the diagnostic process, when full-fledged investigations are not available, as was the case in the author's patient series.