Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.6K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
Breathing01:05

Breathing

65.4K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
65.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cytokine Profiling of Systemic Sclerosis-Related Pulmonary Hypertension.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

Many uncertainties remain in the long-term care of sickle cell disease-pulmonary hypertension.

American journal of respiratory and critical care medicine·2026
Same author

Provider networks for pulmonary hypertension in Massachusetts: implications for improving referrals to expert care.

Annals of the American Thoracic Society·2026
Same author

Risk stratifying systemic sclerosis-related pulmonary hypertension by left atrial strain.

Rheumatology (Oxford, England)·2026
Same author

Acute Exercise Challenge and Airway Dynamics in Youth With Sickle Cell Anemia: A Multicenter Study.

American journal of hematology·2025
Same author

Let's Not Keep Acute Chest Syndrome Under an Umbrella.

American journal of respiratory and critical care medicine·2025

Related Experiment Video

Updated: Mar 10, 2026

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms
02:34

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

2.1K

Sickle cell disease: wheeze or asthma?

Robyn T Cohen1, Elizabeth S Klings2, Robert C Strunk3

  • 1Division of Pediatric Pulmonary and Allergy, Department of Pediatrics, Boston University School of Medicine, 850 Harrison Avenue, Boston, MA 02118 USA.

Asthma Research and Practice
|December 15, 2016
PubMed
Summary

Sickle cell disease (SCD) patients often experience respiratory issues like asthma and wheezing, which are linked to increased health problems. Diagnosing asthma in SCD is challenging due to overlapping symptoms and requires further research for better management.

Keywords:
Airway hyperresponsivenessAirway obstructionAsthmaLung functionPrevalenceSickle cell diseaseWheezing

More Related Videos

Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

1.2K
Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

28.9K

Related Experiment Videos

Last Updated: Mar 10, 2026

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms
02:34

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

2.1K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

1.2K
Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

28.9K

Area of Science:

  • Pulmonary Medicine
  • Genetics
  • Immunology

Background:

  • Sickle cell disease (SCD) is a prevalent genetic disorder impacting over 100,000 Americans, predominantly African Americans.
  • Respiratory complications in SCD significantly increase morbidity and mortality.
  • Wheezing, even without an asthma diagnosis, is increasingly recognized as a potential indicator of SCD severity.

Approach:

  • This review synthesizes current knowledge on asthma, wheezing, and airway obstruction in SCD patients.
  • It examines the links between these respiratory conditions and SCD-related health issues.
  • The review also explores the pathophysiology of airway inflammation in SCD.

Key Points:

  • Asthma diagnosis in SCD is complicated by high rates of wheezing, airway obstruction, and hyperresponsiveness.
  • These respiratory symptoms can occur independently of formal asthma criteria.
  • Understanding these challenges is crucial for accurate diagnosis and effective treatment.

Conclusions:

  • Further research is needed to clarify the epidemiology and pathophysiology of asthma in SCD.
  • Improved diagnostic and management strategies are essential for this vulnerable patient population.
  • Addressing respiratory health is critical for improving outcomes in sickle cell disease.