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Management of cardiovascular disease in aging persons with haemophilia

Roger E G Schutgens1, Michiel Voskuil, Evelien P Mauser-Bunschoten

  • 1Roger E. G. Schutgens, MD, PhD, MSc, Van Creveldkliniek, UMC Utrecht, Heidelberglaan 100 3584CX Utrecht, The Netherlands, Tel: +31 88 7558450, r.schutgens@umcutrecht.nl.

Hamostaseologie
|December 15, 2016
PubMed

Insights

Managing cardiovascular disease in aging hemophilia patients presents challenges. This review covers current knowledge on risk factors, prevalence, and anticoagulation strategies for hemophilia complications.

Area of Science:

  • Cardiology
  • Hematology

Background:

  • Aging hemophilia populations face increasing age-related comorbidities.
  • Cardiovascular disease (CVD) management in hemophilia patients is complex.
  • Prevalence, risk factors, and management of CVD in hemophilia are increasingly understood.

Purpose of the Study:

  • To provide an overview of current knowledge on cardiovascular disease in hemophilia.
  • To highlight challenges in managing hemophilia patients with CVD.
  • To discuss new insights in anticoagulation for hemophilia-related cardiovascular issues.

Main Methods:

  • Literature review of current knowledge on CVD in hemophilia.
  • Analysis of prevalence and risk factors for CVD in hemophilia.
  • Examination of anticoagulation management strategies for atrial fibrillation and coronary ischemia in hemophilia.

Main Results:

  • Hypertension and overweight are common risk factors in hemophilia patients.
  • New insights into anticoagulation for atrial fibrillation and coronary ischemia have emerged.
  • Substantial improvements in understanding CVD in hemophilia have been made.

Conclusions:

  • Cardiovascular disease is a significant medical issue in the aging hemophilia population.
  • Effective management requires addressing common risk factors like hypertension and overweight.
  • Ongoing research provides new strategies for anticoagulation in hemophilia patients with CVD.

Keywords:
anticoagulationcardiovascularhaemophilia

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