Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatal hydrogen sulfide poisoning.

M Campanyà, P Sanz, R Reig

    La Medicina Del Lavoro
    |May 1, 1989
    PubMed
    Summary

    Fatal hydrogen sulfide (H2S) poisoning occurred in two individuals during tank cleaning after polysulfide transport. Autopsies revealed characteristic H2S toxicity, emphasizing the need for strict safety protocols during industrial chemical handling.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An astrocytic cellular model of Lafora disease to study polyglucosan accumulation and inflammation.

    Disease models & mechanisms·2025
    Same author

    P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease.

    Neurobiology of disease·2023
    Same author

    Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans.

    Pharmacological research·2020
    Same author

    Chronic obstructive pulmonary disease (COPD) in Spain and the different aspects of its social impact: a multidisciplinary opinion document.

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2020
    Same author

    Exposure to single and binary mixtures of fullerenes and triclosan: Reproductive and behavioral effects in the freshwater snail Radix balthica.

    Environmental research·2019
    Same author

    In vivo glutamate clearance defects in a mouse model of Lafora disease.

    Experimental neurology·2019

    Area of Science:

    • Toxicology
    • Occupational Health
    • Forensic Pathology

    Background:

    • Hydrogen sulfide (H2S) is a toxic gas commonly encountered in industrial settings, particularly during the handling of sulfur-containing compounds like polysulfides.
    • Accidental H2S poisoning can lead to rapid and severe health consequences, necessitating a thorough understanding of its toxicological profile.

    Observation:

    • Two fatal cases of hydrogen sulfide poisoning are presented, stemming from the cleaning of a tank previously used for polysulfide transport.
    • Autopsies revealed distinctive macroscopic and microscopic findings, including blackish-green pigmentation, pulmonary edema, steatosis, intrahepatic cholestasis, and renal tubular necrosis.

    Findings:

    • Blood sulfide ion concentrations in the affected individuals exceeded 3.5 mg/l, confirming significant H2S exposure.

    Related Experiment Videos

  • The observed pathological changes are consistent with known mechanisms of acute hydrogen sulfide toxicity.
  • Comparison with existing literature highlights the characteristic presentation of fatal H2S poisoning in this context.

    • Implications:

    • These cases underscore the critical importance of implementing robust safety measures and personal protective equipment when working in environments with potential hydrogen sulfide exposure.
    • Proper risk assessment and adherence to safety protocols are essential to prevent fatalities during industrial cleaning operations involving hazardous chemicals.
    • The findings contribute to the medical and forensic understanding of hydrogen sulfide poisoning, aiding in future prevention and investigation efforts.