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Local intraarterial fibrinolysis in acute vertebrobasilar occlusion. Technical developments and recent results
H Zeumer1, H J Freitag, U Grzyska
1Department of Neuroradiology, University Hospital Eppendorf, Hamburg, Federal Republic of Germany.
Neuroradiology
|January 1, 1989
Abstract:
Local intraarterial fibrinolytic therapy (LIF) in patients with acute vertebrobasilar occlusion (AVBO) is a rational and if successful a life saving treatment. The recent progress in this field is determined by the use of microcatheters for superselective basilar artery catheterisation and a "short time, highdose" regimen using 750.000 IU Urokinase in not more than two h. Two out of 7 patients died and 1 did not improve to a better than a locked-in-state. Four patients however survived with excellent outcome.