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Effects of TSLP on obstetrical and gynecological diseases

Yuan Zhang1, Li-Ping Jin1,2

  • 1Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, China.

American Journal of Reproductive Immunology (New York, N.Y. : 1989)
|December 16, 2016
PubMed

Thymic stromal lymphopoietin (TSLP) is produced mainly by epithelial cells and was originally found to stimulate the growth and activation of B cells, but it is now shown to function on both hematopoietic and non-hematopoietic cell lineages. Despite a number of studies focusing on the role of TSLP in Th2 response for allergic disorders, it is becoming increasingly evident that TSLP may also be involved in multiple other disease states. This review will focus on recent advances on the effects of TSLP on obstetrical and gynecological diseases, including pregnancy failure, endometriosis, and cervical cancer.

Keywords:
cervical cancerendometriosispregnancythymic stromal lymphopoietin (TSLP)

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