Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

CRISPR01:59

CRISPR

58.5K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
58.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adverse Newborn Outcomes by Insurance Status Among Patients with Severe Maternal Morbidity in Maryland: 2020-2023.

Healthcare (Basel, Switzerland)·2026
Same author

Optimizing genetic engineering approaches for protein loading into bacterial extracellular vesicles for vaginal drug delivery.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Targeting SAA expression via siRNA mitigates preterm birth induced by maternal inflammation.

Frontiers in pharmacology·2026
Same author

A model for prevention: applying lessons from Group B Streptococcus to Staphylococcus aureus in very low birth weight neonates.

Journal of perinatology : official journal of the California Perinatal Association·2025
Same author

Serum soluble-fms-like tyrosine kinase 1-to-placental growth factor ratio on Elecsys immunoassay platform predicts preeclampsia with severe features in hospitalized women with hypertensive disorders of pregnancy.

American journal of obstetrics and gynecology·2025
Same author

Pregnancy reduces COVID-19 vaccine immunity against novel variants.

NPJ vaccines·2025

Related Experiment Video

Updated: Mar 10, 2026

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids
09:18

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

Published on: September 19, 2017

11.0K

Zika virus: Future reproductive concerns.

Christopher M Novak1, Jeanne S Sheffield1, Irina Burd1

  • 1Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Integrated Research Center for Fetal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

American Journal of Reproductive Immunology (New York, N.Y. : 1989)
|December 16, 2016
PubMed
Summary

Zika virus (ZIKV) transmission concerns reproductive health specialists due to fetal abnormalities. Comparing ZIKV to hepatitis C virus (HCV) and bovine viral diarrhea virus (BVDV) may clarify ZIKV

Keywords:
Zika viruscongenital infectionviral persistence

More Related Videos

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult
09:39

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Published on: April 26, 2018

9.2K
Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
09:11

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

21.6K

Related Experiment Videos

Last Updated: Mar 10, 2026

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids
09:18

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

Published on: September 19, 2017

11.0K
Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult
09:39

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Published on: April 26, 2018

9.2K
Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
09:11

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

21.6K

Area of Science:

  • Virology and Reproductive Health
  • Comparative Teratology and Epidemiology

Background:

  • The global spread of Zika virus (ZIKV) presents a significant public health challenge.
  • ZIKV's sexual and transplacental transmission routes are of particular concern for reproductive specialists, leading to fetal congenital abnormalities.
  • Hepatitis C virus (HCV) and bovine viral diarrhea virus (BVDV) are known flaviviruses with similar transmission and teratogenic potentials.

Purpose of the Study:

  • To review the current literature on ZIKV vertical transmission and neuro-teratogenicity.
  • To compare ZIKV's characteristics with those of HCV and BVDV.
  • To explore potential persistent infection of ZIKV in offspring by drawing parallels with HCV and BVDV.

Main Methods:

  • Literature review of scientific articles on ZIKV, HCV, and BVDV.
  • Comparative analysis of transmission routes, teratogenic effects, and persistent infection capabilities.
  • Synthesis of existing knowledge to address questions regarding ZIKV's impact on fetal development and offspring health.

Main Results:

  • ZIKV shares transmission similarities (sexual, transplacental) and neuro-teratogenic potential with BVDV.
  • HCV and BVDV are established causes of vertical transmission and persistent infections in offspring.
  • The comparison highlights potential areas of concern for ZIKV, including persistent infection.

Conclusions:

  • Understanding flaviviruses like HCV and BVDV provides a framework for investigating ZIKV's reproductive and developmental impacts.
  • Further research is warranted to confirm and understand the potential for persistent ZIKV infection in newborns.
  • Comparative virology is crucial for anticipating and managing public health threats posed by emerging viruses like ZIKV.