Related Experiment Video
Updated: Mar 10, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
[Validation and clinical application of MammaPrint® in patients with breast cancer]
Ernesto Roberto Sánchez-Forgach1, Ubaldo Carpinteyro-Espín2, Jorge Alberto Alemán-Áviles3
1Servicio de Cirugía Oncológica, Mastológica Lomas, Centro de Estudios Mastológicos, S.A. de C.V., Ciudad de México, México.
Background:
In recent years, advances in molecular biology have resulted in innovations in breast cancer diagnostics and therapeutics. The development of genomics has revolutionized our understanding of this disease. MammaPrint® was developed as a diagnostic tool to predict risk of breast cancer recurrence using the expression of 70 genes altering the clinicopathologic paradigm of selection of patients for adjuvant cytotoxic chemotherapy.
Materials And Methods:
A study of stage i-ii breast cancer patients on whom the MammaPrint® genomic assay was performed.
Results:
The use of the MammaPrint® assay was a decisive factor for the recommendation of adjuvant treatment with chemotherapy and/or hormone therapy in patients with high risk for relapse. In our group, the patients with low-risk have not presented local or systemic recurrences DISCUSSION: The determination of the genetic characteristics and its alterations in breast cancer, is fundamentally important for a better identification of risk, as well as a better selection of cancer therapy.
Conclusion:
MammaPrint® is an effective study to determine risk of recurrence of in early stage breast cancer.
