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Related Experiment Video

Updated: Mar 10, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

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Coronary Embolization Caused by Pleomorphic Lung Carcinoma.

Tadashi Murai¹, Taishi Yonetsu, Mitsuaki Isobe

¹Department of Cardiology, Tsuchiura Kyodo General Hospital, Japan.

Internal Medicine (Tokyo, Japan)

|December 17, 2016

Summary

A rare case of heart attack (ST-segment elevation myocardial infarction) was caused by lung cancer spreading through the pulmonary vein. Doctors removed a tumor embolus during treatment, successfully restoring blood flow.

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Published on: October 25, 2024

Area of Science:

Cardiology
Oncology
Pulmonology

Background:

ST-segment elevation myocardial infarction (STEMI) is a critical condition usually caused by coronary artery thrombosis.
Pulmonary vein invasion by tumors is uncommon and can lead to complex cardiovascular presentations.

Observation:

A 73-year-old male presented with acute chest pain diagnosed as STEMI.
Intracoronary aspiration retrieved a worm-like object, and revascularization was successful.
Imaging revealed a large right upper lobe pulmonary mass with direct pulmonary vein invasion.

Findings:

Histopathology confirmed the aspirated object was pleomorphic lung carcinoma.
The STEMI was attributed to tumor embolization from the lung mass into the left coronary artery via the pulmonary vein.

Implications:

This case highlights an unusual mechanism of myocardial infarction secondary to malignant tumor embolization.
It underscores the importance of considering rare etiologies in STEMI, especially with concurrent pulmonary findings.
Early diagnosis and intervention are crucial for managing such complex oncological and cardiovascular emergencies.