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Updated: Mar 10, 2026

The ITS2 Database
Published on: March 12, 2012
Extracorporeal Life Support Organization Registry International Report 2016
Ravi R Thiagarajan1, Ryan P Barbaro, Peter T Rycus
1From the *Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts; †Department of Pediatrics, C.S. Mott Children's Hospital, Ann Arbor, Michigan; ‡Extracorporeal Life Support Organization, Ann Arbor, Michigan; §Department of Cardiac Surgery, Seattle Children's Hospital, Seattle, Washington; ¶Departments of Medicine, Pediatrics and Emergency Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana; and ‖Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia.
Abstract:
Data on extracorporeal life support (ECLS) use and survival submitted to the Extracorporeal Life Support Organization's data registry from the inception of the registry in 1989 through July 1, 2016, are summarized in this report. The registry contained information on 78,397 ECLS patients with 58% survival to hospital discharge. Extracorporeal life support use and centers providing ECLS have increased worldwide. Extracorporeal life support use in the support of adults with respiratory and cardiac failure represented the largest growth in the recent time period. Extracorporeal life support indications are expanding, and it is increasingly being used to support cardiopulmonary resuscitation in children and adults. Adverse events during the course of ECLS are common and underscore the need for skilled ECLS management and appropriately trained ECLS personnel and teams.
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