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Updated: Mar 10, 2026

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
Acute hepatitis E presenting with clinical feature of autoimmune hepatitis
Ishan Patel1, Rafael Ching Companioni2, Raghav Bansal2
1Internal Medicine, Icahn School of Medicine (Elmhurst) Program, Elmhurst, NY, USA; ishan811@gmail.com.
Abstract:
A 32-year-old immigrant man presented with new onset jaundice. His past medical history was significant for type 2 diabetes mellitus, hypertension, and hyperlipidemia. His initial laboratory finding and liver biopsy were suggestive of autoimmune hepatitis (AIH). The plan was to start steroids pending negative results for viral serology, but it came back positive for hepatitis E virus. The patient's liver function test and clinical condition improved significantly on conservative management over a period of 1 month. Therefore, we suggest testing for hepatitis E especially in immigrants or recent travelers to endemic areas who presents with clinical features suggestive of AIH.
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