Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

8.7K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
8.7K
Drug Elimination: The Concept of Clearance01:06

Drug Elimination: The Concept of Clearance

4.2K
Drug elimination refers to removing drugs from the body, either through urine by the kidneys or through bile by the liver. Drug clearance is a pharmacokinetic parameter that measures the efficiency of drug removal from the bloodstream within a specific time frame. It is calculated as the rate at which a drug is eliminated from plasma divided by the plasma concentration of the drug.
Drug clearance is not limited to renal excretion but encompasses all organs involved in drug elimination,...
4.2K
Limits at Infinity01:24

Limits at Infinity

381
The function that decreases as the input becomes very large provides a clear example of how mathematical functions can behave at extreme values. When the input increases continuously, the output becomes smaller and smaller, getting closer to a particular fixed value. Although the output never actually reaches this value, it moves nearer to it without limit. This behavior is a fundamental concept in understanding how functions behave as the input grows indefinitely. The graphical representation...
381
Detection of Gross Error: The Q Test01:00

Detection of Gross Error: The Q Test

7.2K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
7.2K
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

85
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
85
Errors In Hypothesis Tests01:14

Errors In Hypothesis Tests

6.1K
When performing a hypothesis test, there are four possible outcomes depending on the actual truth (or falseness) of the null hypothesis and the decision to reject or not.
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

The Safest Car Seat for Your Child.

Consumer reports·2016
Same journal

An Essential Heart-Surgery Device Has a Rare But Deadly Side Effect.

Consumer reports·2016
Same journal

Colon cancer runs in my family: Should I get a genetic test? I worry that'll affect my insurance.

Consumer reports·2016
Same journal

How to Survive a High-Deductible Health Plan. Is your insurance giving you a bad case of sticker shock? Here are ways to ease the pain.

Consumer reports·2016
Same journal

Your Health Is Priceless.

Consumer reports·2016
Same journal

Fighting Merger Mania in Health Insurance.

Consumer reports·2016
See all related articles

Related Experiment Video

Updated: Mar 10, 2026

High-Resolution Respirometry in a Small-Volume Chamber
10:08

High-Resolution Respirometry in a Small-Volume Chamber

Published on: July 25, 2025

1.5K

Zero Tolerance.

Hallie Levine

    Consumer Reports
    |December 18, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Hospital-acquired infections are deadly but preventable. This investigation reveals which hospitals are failing to protect patients from dangerous bacteria and offers safety tips.

    More Related Videos

    Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
    11:20

    Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

    Published on: December 11, 2009

    12.3K
    Author Spotlight: High-Throughput Toxicity Screening Using Zebrafish Embryo Startle Response Assay
    06:25

    Author Spotlight: High-Throughput Toxicity Screening Using Zebrafish Embryo Startle Response Assay

    Published on: January 12, 2024

    2.3K

    Related Experiment Videos

    Last Updated: Mar 10, 2026

    High-Resolution Respirometry in a Small-Volume Chamber
    10:08

    High-Resolution Respirometry in a Small-Volume Chamber

    Published on: July 25, 2025

    1.5K
    Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
    11:20

    Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

    Published on: December 11, 2009

    12.3K
    Author Spotlight: High-Throughput Toxicity Screening Using Zebrafish Embryo Startle Response Assay
    06:25

    Author Spotlight: High-Throughput Toxicity Screening Using Zebrafish Embryo Startle Response Assay

    Published on: January 12, 2024

    2.3K

    Area of Science:

    • Healthcare-associated infections (HAIs)
    • Infection prevention and control
    • Patient safety in hospitals

    Background:

    • Hospital-acquired infections (HAIs) pose a significant threat to patient safety.
    • Despite progress, preventable bacterial infections remain a concern in healthcare settings.
    • Effective infection control protocols are crucial for reducing patient morbidity and mortality.

    Purpose of the Study:

    • To identify hospitals with high and low rates of preventable hospital-acquired infections.
    • To investigate the factors contributing to the persistence of dangerous bacteria in healthcare environments.
    • To provide actionable information for patients and families to enhance their safety.

    Main Methods:

    • Analysis of national healthcare-associated infection (HAI) data.
    • Comparative assessment of infection control practices across different hospital institutions.
    • Review of patient safety reports and public health surveillance data.

    Main Results:

    • Significant variations in preventable infection rates were observed among hospitals nationwide.
    • Certain healthcare facilities demonstrate superior performance in infection prevention and control.
    • A subset of hospitals continues to exhibit unacceptably high exposure rates to dangerous bacteria.

    Conclusions:

    • There is a critical need for improved adherence to infection prevention protocols in many healthcare facilities.
    • Publicly available data can empower patients to make informed decisions about hospital safety.
    • Enhanced vigilance and standardized practices are essential to eliminate preventable hospital-acquired infections.