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[A new sustained-release formulation of trazodone for treatment of minor psychopathological depression. A controlled
Abstract:
In a controlled study the activity and tolerance of two formulations of trazodone (traditional and controlled-release) were compared in a group of 30 geriatric patients with minor anxious-depressive manifestations. The results showed a better activity with the controlled-release formulation (a single dose administered in the evening) on sleep disturbances as far as their effects on the psychopathological picture is concerned or on tolerance.