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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Related Experiment Video

Updated: Mar 10, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Drug-induced Angle-Closure Glaucoma.

Aruj K Khurana1, Bhawna Khurana2, Ashok K Khurana2

  • 1Senior Professor, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.

Journal of Current Glaucoma Practice
|December 20, 2016
PubMed
Summary
This summary is machine-generated.

Drug-induced angle-closure glaucoma is a preventable cause of blindness. Early detection through high suspicion and imaging like ultrasound or OCT is crucial for timely treatment and sight preservation.

Keywords:
Acute angle closureDrug-induced glaucoma.

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Area of Science:

  • Ophthalmology
  • Medical Diagnostics

Background:

  • Drug-induced angle-closure glaucoma is a significant clinical entity.
  • It represents a preventable cause of potential blindness.

Approach:

  • This review emphasizes the importance of a high index of suspicion in susceptible individuals.
  • It highlights the role of imaging modalities such as ultrasound biomicroscopy (UBM), ultrasound, or anterior segment optical coherence tomography (OCT) for confirmation.

Key Points:

  • Prompt diagnosis is essential to prevent vision loss.
  • Appropriate imaging confirms the condition.
  • Timely therapeutic intervention is critical.

Conclusions:

  • A high index of suspicion combined with advanced imaging can effectively manage drug-induced angle-closure glaucoma.
  • This approach alleviates the threat to sight and facilitates appropriate treatment.