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Updated: Mar 9, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Combined NOTES total mesorectal excision and single-incision laparoscopy principles for conservative proctectomy: a
H Meillat1, C de Chaisemartin2, F Poizat3
1Department of Digestive Surgical Oncology, Paoli Calmettes Institute, 232 Bd de Sainte Marguerite, 13009, Marseille, France. meillath@ipc.unicancer.fr.
This study shows that combining transanal endoscopic total mesorectal excision (TME) with single-port abdominal surgery is a safe and effective minimally invasive option for low rectal cancer, offering good survival rates.
Area of Science:
- Colorectal Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Standard laparoscopic surgery for low rectal cancer presents challenges.
- Transanal endoscopic total mesorectal excision (TME) is a feasible approach with low conversion rates.
- Combining transanal and single-port abdominal approaches may reduce trauma and improve recovery.
Purpose of the Study:
- To evaluate the short- and mid-term outcomes of a combined transanal endoscopic TME and single-port abdominal surgery technique.
- To assess the feasibility, safety, and efficacy of this novel minimally invasive approach for low rectal cancer.
Main Methods:
- Prospective single-centre study of 41 consecutive patients with low rectal cancer undergoing conservative proctectomy with manual coloanal anastomosis.
- Data collected between January 2012 and April 2015.
- Involved a combined transanal endoscopic TME and single laparoscopic ileostomy-site proctectomy.
Main Results:
- Low conversion rate to open surgery (2.4%).
- Median operating time of 358.5 minutes.
- High rates of complete or nearly complete specimens (100%) with a 4.9% circumferential resection margin positivity.
- Overall survival of 97.5% and disease-free survival of 80.5% at a median follow-up of 29 months.
- Stoma-free survival rate of 95.1%.
Conclusions:
- The combined technique is a promising minimally invasive approach for low rectal cancer.
- It achieves good oncological outcomes and high stoma-free survival.
- This approach offers potential benefits in terms of reduced wound trauma and faster recovery.
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