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Updated: Mar 9, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Artificial heart pumps: bridging the gap between science, technology and personalized medicine by relational medicine
1Graduate School of Education & Information Studies & David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Abstract:
In the US population of 300 million, 3 million have heart failure with reduced ejection fraction and 300,000 have advanced heart failure. Long-term mechanical circulatory support will, within the next decade, be recommended to 30,000 patients annually in the USA, 3000 undergo heart transplantation annually. What do these advances mean for persons suffering from advanced heart failure and their loved ones/caregivers? In this perspective article, we discuss - by exemplifying a case report of a 27-year-old man receiving a Total Artificial Heart - a practice concept of modern medicine that fully incorporates the patient's personhood perspective which we have termed Relational Medicine™. From this case study, it becomes apparent that the successful practice of modern cardiovascular medicine requires the person-person encounter as a core practice element.
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