[Applied pharmacology of anesthetics]

Inhalation anesthetics, intravenously applied anesthetics, opiates, muscle relaxants and local anesthetics are the most commonly used anesthetic drugs. From the direct anesthetic effects interactions with other organ systems and functions, especially those involved in vital functions such as the pulmonary and cardio-vasculary systems, must be distinguished. Although the safety-margins for individual drugs vary, side effects are minimal on appropriate dosage and use. Substance-related complications, such as severe hepatic damage or malignant hyperthermia, are rare. Procedure-related differences (general or local anesthesia) were not found for post-operative morbidity and mortality, nor was there a detectable impairment of concentration and mnestic performance.