Related Experiment Videos
[Garcin syndrome--a case report]
Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|September 19, 1989
Summary
This case study details a 68-year-old woman with Garcin syndrome caused by breast cancer skull metastasis. It highlights skull base tumors as a common cause of multiple cranial nerve deficits.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- Garcin syndrome, characterized by unilateral multiple cranial nerve palsies, is often associated with skull base pathologies.
- Metastatic disease, particularly from breast carcinoma, can present as a cause of skull base destruction and subsequent cranial nerve involvement.
Observation:
- A detailed case of a 68-year-old woman presenting with Garcin syndrome due to a skull metastasis from mammary carcinoma is presented.
- The patient exhibited unilateral multiple brain nerve lesions, consistent with skull base compromise.
Findings:
- Skull base destruction, a hallmark of metastatic disease or primary bone tumors, was evident.
- Plain X-rays and computed tomography (CT) scans were instrumental in visualizing the osseous destruction.
Implications:
- This case underscores the importance of considering metastatic disease in the differential diagnosis of Garcin syndrome.
- Early detection of skull base destruction through imaging is crucial for timely management of patients with cranial nerve deficits.