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Hypernatremic Dehydration in Breastfed Term Infants: Retrospective Evaluation of 159 Cases
Elif Ünver Korğalı1, Meriç Kaymak Cihan2, Tahir Oğuzalp3
11 Department of Pediatrics, Cumhuriyet University Faculty of Medicine , Sivas, Turkey .
Insights
Hypernatremic dehydration (HD) in breastfed infants is linked to fever and oral dryness. Prompt treatment is crucial to prevent severe complications in newborns.
Area of Science:
- Neonatology
- Pediatrics
- Public Health
Background:
- Hypernatremic dehydration (HD) is a serious condition in term breastfed infants.
- Understanding its frequency, risk factors, and complications is vital for prevention and management.
Purpose of the Study:
- To determine the incidence, clinical presentation, risk factors, and complications of HD in term breastfed infants.
- To explore preventive strategies for hypernatremic dehydration.
Main Methods:
- Retrospective analysis of 159 term breastfed infants hospitalized for HD between 2009-2014.
- Infants were categorized into two groups based on serum sodium (Na) levels: Group 1 (146-149 mEq/L) and Group 2 (≥150 mEq/L).
Main Results:
- Fever (67.9%) and oral mucosal dryness (76%) were the most common presenting complaints and findings.
- Higher serum Na levels correlated with increased weight loss, longer hospital stays, and higher body temperature.
- Group 2 infants experienced a longer Na normalization period and higher incidence of bradycardia.
Conclusions:
- Hypernatremic dehydration is a significant neonatal condition requiring appropriate and timely treatment.
- Early recognition and intervention are essential to mitigate potential serious complications in affected infants.
Objectives:
The aim of this study was to reveal the frequency, presenting complaints, risk factors, complications, and ways for prevention of hypernatremic dehydration (HD) among term breastfed infants.
Methods:
The files of 159 breastfed term infants hospitalized because of HD between the years 2009 and 2014 were examined retrospectively in the Neonatal Intensive Care Unit of Sivas State Hospital, Turkey. The patients were classified according to serum sodium (Na) levels, group 1 (Na: 146-149 mEq/L, n = 68) and group 2 (Na ≥150 mEq/L, n = 91).
Results:
The most common complaint was fever (67.9%), and the most common physical finding was oral mucosal dryness (76%). There were positive correlations between serum Na levels and weight loss, hospital stay, admission age, admission to neonatal unit after discharge, serum urea levels, and body temperature (p < 0.05). The normalization period of Na levels was significantly longer (21.7 ± 8.8 versus 29.3 ± 17.8 hours, p = 0.03), and Na reduction rate was faster in group 2 (0.41 ± 0.3 versus 0.50 ± 0.3 mEq/L/hour, p = 0.02). Bradycardia was seen more commonly in group 2 (1.5% versus 16.5%, p = 0.002).
Conclusions:
HD is a significant condition that should be treated appropriately to avoid serious complications.
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